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MONDAY JUNE, 19

 

S1. Pharmacology and toxicology of drug transporters: recent advances

Chairs: Ann Daly, Newcastle University (UK)

          Dan Antoine, University of Liverpool (UK)

11:00-11:30      

Prof. Matthias Schwab, IKP Stuttgart (Germany)

"Pharmacogenomics and epigenetic alteration of membrane transporters"

11:30-12:00

Dr. Aleksandra Galetin, Manchester University (UK)

“PBPK modelling of drug transporters to facilitate individualized dose prediction"
12:00-12:30

Dr. Jose Manautou, University of Connecticut (USA)

“ABC transporters in drug-induced liver injury”

12:30-13:00

Dr. Shiew-Mei Huang, FDA (USA)

"Scientific Perspective on the Evaluation of Transporter-based Drug-drug Interactions"

 

S2. Pain

Chairs: Jose Manuel Baeyens, University of Granada (Spain)

          Esther Berrocoso, University of Cadiz (Spain)Esteve blue sin baseline-01
11:00-11:30

Prof. Victor Mayoral, Bellvitge Hospital (Spain)

"Pharmacological associations in pain. A real life scenario"

11:30-12:00

Dr. Esther Berrocoso, University of de Cádiz (Spain)

“Implication of noradrenaline in pain and its emotional consequences”               

12:00-12:30

Prof. Jose Manuel Baeyens, University of Granada (Spain)

"Sigma-1 receptor blockade unmask peripheral opioid analgesia"
12:30-13:00    

Dr. Enrique Portillo-Salido, Laboratorios Esteve (Spain)

“Animal Models of Pain: Beyond the Evaluation of Reflexes”

 

S3. Ichaemia and Reperfussion

Chairs: Ana Planas, IDIBAPS/CSIC (Spain)

          Mhairi I. Macrae, University of Glasgow (UK) 
11:00-11:30

Prof. María Ángeles Moro, Universidad Complutense de Madrid (Spain)

"Cerebrovascular pathology: novel pharmacological strategies"
11:30-12:00

Dr. Sergio Amaro, IDIBAPS/CSIC (Spain)

"Novel therapies for acute ischemic stroke: from pharmacological neuroprotection to vasculoprotection"

12:00-12:30

Prof. Mhairi I. Macrae, University of Glasgow (UK)

"Oxycyte: an intravenous oxygen carrier capable of diagnosing and treating acute ischaemic stroke"
12:30-13:00                

Dr. Antonio Rodríguez Sinovas, VHIR (Spain)

“Protection against myocardial reperfusion injury by targeting mitochondrial succinate dehydrogenase”

 

S4. G Protein-coupled receptors pharmacology

Chairs: Ian McGrath, University of Glasgow (UK)

          Leonardo Pardo, Autonomous University of Barcelona (Spain)Tocris-Biotechne-logo-rgb-cropped

14:30- 15:00              

Prof. Ian McGrath, University of Glasgow, (UK)

The drug invention template: from "crafted round the natural hormone" to sculpted to fit the receptor

15:00-15.30

Prof. Leonardo Pardo, University Autonomous of Barcelona, Spain

"New approaches to modulate GPCRs"

15:30-16:00

Dr. Víctor Fernández- Dueñas, University of Barcelona, Spain

"Optopharmacology: lighting up G protein-coupled receptors"

16:00-16:30

Dr. Peter McCormick, University of Surrey (UK)

"GPCR Heterodimers: What are they good for and how do they work?"

 

S5. Cardiovascular and smooth muscle pharmacology

Chairs: Juan Tamargo, Universidad Complutense de Madrid (Spain)

          Mª Pilar D'Ocon, Valencia University (Spain)
14:30-15:00

Prof. Juan Tamargo, Universidad Complutense de Madrid (Spain)

"New drugs in the treatment of heart failure: hope or hype?”

15:00-15:30

Ana Mª Briones, University Autonomous of Madrid (Spain)

"Novel mediators of inflammation in vascular damage in hypertension"

15:30-16:00

Prof. Francisco Pérez-Vizcaíno, Universidad Complutense de Madrid (Spain)

"Drugs for pulmonary hypertension: old stories of partial success, partial failure and new perspectives"

16:00-16:30       

Prof. Guillermo Zalba Goñi, Navarra University (Spain)

"Pleiotropic actions of Losartan metabolites in hypertension"

 

S6. Natural Products in Pharmacology

Chairs: Salvador Fudio, Pharmamar (Spain)

          Rafael de la Torre, IMIM (Spain)

14:30-15.00            

Prof. Salvador CañigueralUniversity of Barcelona (Spain)

"Quality of Herbal Medicinal Products: contribution of the European Pharmacopoeia"

15:00-15:30

Prof. Rafael de la Torre, IMIM (Spain)

"Flavonoids in the treatment of mental disorders"

15:30-16:00

Dr. Salvador Fudio, PharmaMar (Spain)

"Marine derived medicines for the treatment of cancer: the experience of PharmaMar"

16:00-16:30     Prof. Javier Fernández Ruiz, Universidad Complutense de Madrid (Spain)

"Development of neuroprotective therapies with phytocannabinoids for neurodegenerative disorders"

 

TUESDAY JUNE, 20

 

S7. Being in the right place in the right time: Targeting Oxidate Stress 

Chair: Martina Schmidt, University of Groningen (The Netherlands)

11:00-11:30 

Dr. Steven Charlton, University of Nottngham (UK)

"Measuring ligand concentration where it matters: Assessing the “micro PK/PD” of adenosine A2a receptor ligands"
11:30-12:00

Dr. Paul A. Kirkham, Imperial College London (UK)

“Molecular and function impact of oxidative stress in COPD”

12:00-12:30

Dr. Amalia Dolga, University of Groningen (The Netherlands)

"Targeting mitochondria in oxidative stress via modulation of potassium channels"

12:30-13:00          

Prof. Darryl Knight, University of Newcastle (Australia)

"Mitochondrial dysfunction is a key driver of fibroblast senescence. So what do we target?"

 

S8. Inflammation

Chair: Mª Jesús Sanz, University of Valencia, (Spain)

11:00-11:30                           

Prof.  Aleksandar Ivetic, King's College London (UK)

"L-selectin shedding is the ³go² signal for neutrophil effector function: a potential therapeutic target in sterile injury”

11:30-12:00

 Prof. Concha Peiró, Autonomous University of Madrid (Spain)

“Adipocytokines: novel therapeutic targets in endothelial dysfunction and vascular inflammation?

12:00-12:30

Prof. María Jesús Sanz, University of Valencia (Spain)

"CXCL16/CXCR6 axis blockade impairs metabolic syndrome-associated endothelial dysfunction and abdominal aortic aneurysm (AAA) development"

12:30-13:00       

Two oral presentations to be selected from submitted abstracts

 

S9. Psychopharmacology

Chairs: Javier J. Meana, Pais Vasco University (Spain)

           Juan Carlos Leza, Universidad Complutense de Madrid (Spain)
11:00-11:30

Dr. Roger Prades, IPROTEOS (Spain)

"The prolyl oligopeptidase inhibitor IPR-19 ameliorates cognitive deficits in mouse models of schizophrenia"

11:30-12:00

Dr. Luis F. Callado, Pais Vasco University (Spain)

"Role of serotonin 5-HT3 receptors in the treatment of depressive disorders"

12:00-12:30

Prof. Magi Farré, University Autonomous of Barcelona (Spain)

"Pharmacology of new psychoactive substances"

12:30-13:00      

Dr. Lucile Capuron, University of Bourdeaux (France)

"Inflammatory processes in depression"

 

 

S10. Therapeutic Innovation 

Logo AZChairs: Eva Martínez Moragon, Hospital Universitario Dr Peset (Valencia, Spain)

14:30-15:00

 Dr. Lina Badimon

15:00-15:30       

 Dr. Eva Martinez Moragon, Hospital Universitario Dr Peset, (Valencia, Spain)

15:30-16:00

 Dr. Luis De la Cruz Moreno

16:00-16:30

 Dr. Alfonso Soto, Gerencia de Gestión Integradada de A Coruña (Spain)

 

S11. Gastrointestinal and Hepatic Pharmacology

Chair: Jordi Bruix, CIBEREHD, (Spain)

         Marcel Jiménez, Autonomous University of Barcelona (Spain)     cibereh 1

14.30-15:00   

Prof. Marçal Pastor-Anglada, IBUB, University of Barcelona & CIBERehd (Spain)

"The importance of the transportome in hepatic and gastrointestinal diseases"

15:00-15:30

Prof. Mª Luz Martínez Chantar, University of the Basque Country & CIBERehd (Spain)

"Farmacological targets for NASH"

15:30-16:00

Prof. Bruno Sangro, University of Navarra & CIBERehd

"Immune therapy of liver cancer"

16:00-16:30

Prof. Marcel Jiménez, Autonomous University of Barcelona & CIBERehd (Spain)

"Purine receptors and smooth muscle function in the Gastrointestinal Tract”

 

S12. Teaching Pharmacology

Chairs: Silvia Sánchez, University of Barcelona (Spain)

          Josep Eladi Baños, Pompeu Fabra University (Spain)
14:30-15:00   

Prof. Josep Eladi Baños, Pompeu Fabra University (Spain)

"Are TV medical dramas useful to teach clinical pharmacology? An empirical study using House M.D"

15:00-15:30

Dra. Marisa Ferrándiz, University of Valencia (Spain)

“Inter-universitary network for innovative education in Pharmacology: a common space to improve learning?”

15:30-16:00

Dr. Silvia Sánchez, University of Barcelona (Spain)

“An experience of using E-learning in the teaching of pharmacology.”

16:00-16:30          

A. Fernández, T. Ignatova, O. Yashchenko, Medical School Students, University of Barcelona, (Spain)

"An academic service-learning activity in higher education to promote responsible use of antibiotics"

 

WEDNESDAY JUNE, 21

 

 

S13. Neuropharmacology 

Chairs: Olga Valverde, Pompeu Fabra University (Spain)

          Maruja Hurlé, Cantabria University (Spain)

09:00-09:30           

Dr. Julia García- Fuster, Illes Balears University, Spain

"Vulnerability factors that predispose to cocaine addiction"

09:30-10:00     

Dr. Mónica Tramullas, Cantabria University, Spain

"Potential clinical value of microRNA‐30c as biomarker and therapeutic target for neuropathic pain"

10:00-10:30

Prof. Olga Valverde, Pompeu Fabra University, Spain

"Behavioral and molecular alterations induced by maternal alcohol binge consumption in offspring mice"

10:30-11:00

Prof. Francisco Artigas, IDIBAPS/CSIC, Spain

"Therapeutic potential of conjugated siRNAs for the treatment of major depressive disorder"

 

S14. Pharmacology of Anti-Cancer Drugs

Chair:Ramón Salazar, IDIBELL, ICO, University of Barcelona (Spain)

09.00-09:30 

Dr. José Alfón, Ability Pharmaceuticals (Spain)

“ABTL0812 an autophagy-anticancer drug in Phase II clinical trials that inhibits PI3K/Akt/mTOR pathway by inducing TRIB3 expression”

09:30-10:00 Dr. Josep Maria Piultas, IDIBELL, ICO, University of Barcelona (Spain)
10:00-10:30 To be Announced
10:30-11:00                   Dr. Ernest Nadal, IDIBELL, ICO, University of Barcelona

 

S15. JAK.STAT signalling: new targets and therapeutics for multiple diseases

Chairs: Tim Palmer, Bradford (UK)

          Ana P. Costa-Pereira, Imperial College (UK)
09:00-09:30   

Prof. Simon Jones, Cardiff University (UK)

"Inflammatory re-tuning of IL-6 mediated Jak-STAT signaling"

09:30-10:00

Prof. Cristine Watson, University of Cambridge (UK)

"The STAT3 paradox in breast cancer: an inducer of cell death and an oncogene"

10:00-10:30

Prof. Stefan Constantinescu, Brussels (Belgium)

"JAK-STAT Pathway in Myeloproliferative Neoplasms: from JAK2 V617F to Calreticulin Mutants"

10:30-11:00     

Prof. Veronica Sexl, Medical University of Vienna (Austria)

"Targeting STAT5 in leukemogenesis – what’s new?"